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Clinical feature and treatment of bisphosphonate-related osteonecrosis of jaw about oral bisphosphonate administrated patients: case reports

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Ãֿ켺, À±ÇöÁß, ÀÌ»óÈ­,
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Ãֿ켺 ( Choi Woo-Sung ) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ¿©Àǵµ¼º¸ðº´¿ø ±¸°­¾Ç¾È¸é¿Ü°ú
À±ÇöÁß ( Yoon Hyun-Joong ) - °¡Å縯´ëÇб³ ¿©Àǵµ¼º¸ðº´¿ø ±¸°­¾Ç¾È¸é¿Ü°ú
ÀÌ»óÈ­ ( Lee Sang-Hwa ) - °¡Å縯´ëÇб³ ¿©Àǵµ¼º¸ðº´¿ø ±¸°­¾Ç¾È¸é¿Ü°ú

Abstract


Bisphosphonates are used effectively for many medical conditions, such as multiple myeloma, Paget¡¯s disease, osteoporosis, etc. However, recently, osteonecrosis of the jaw was observed in patients receiving long-term bisphosphonate therapy, including oral administration. This osteonecrosis is refractory, and complete recovery is not guaranteed despite a standard treatment protocol being established by many associations related to oral and maxillofacial surgery. The treatment outcome of oral bisphosphonate-related osteonecrosis of jaw (BRONJ) is reported with a review of the relevant literature

Å°¿öµå

Bisphosphonate; Osteonecrosis; Osteoporosis

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